Which of the following would result in edema?
- Hypotension, causing a decrease in tissue fluid at the arteriolar ends of capillaries.
- Decreased tissue protein concentration, causing an increase in osmosis of interstitial fluid into capillaries.
- Increased plasma protein concentration, causing an increase in osmosis of interstitial fluid into capillaries.
- Obstruction of lymphatic vessels, blocking lymphatic drainage.
Option 4 is correct.
Edema is known as the swelling when the fluid accumulates in the interstial space from the intravascular compartment.
Normally when any fluid from the capillaries or intervascular compartments comes into this space, this is taken up by the lymphatic vessels and recirculated back into the intervascular compartments. But if there is any obstruction of these lymphatic vessels, it leads to blockage of the lymphatic drainage. Now this fluid accumulates in the extravascular spaces cauing swelling of that particular part of the body where it accumulates.
So obstruction of lymphatic vessels, blocking lymphatic drainage would result in edema.